Saturday, 31 December 2011

You thought 2011 was tough? (Reuters)

NEW YORK (Reuters) ? Shaky Europe. Political gridlock. Volatile markets.

Familiar themes for those who lived through 2011, and investors should be ready to revisit them next year.

With a spiraling debt crisis in Europe, political upheaval around the world, and crumbling creditworthiness in major industrial nations, 2011 was a tough year to know where to invest. 2012 is unlikely to offer much respite.

The S&P 500, a measure of the biggest U.S. companies' market value, spent much of the year getting pushed up and down, flummoxing shorts and longs - and scaring Moms and Pops away from stocks. It ended the year at 1,257.60, down a mere 0.04 of a point.

But the S&P 500's tepid performance was encouraging, compared with other world equity markets. The United States may still be seen as a safe haven, though even that looks uncertain.

For every rally built on improving economic figures this year, selloffs were never far away on worries the European debt crisis would eventually drag the continent into a recession and perhaps the United States as well. That could continue in 2012.

China and other fast-growing emerging markets can no longer be leaned on as those economies slow. In 2011's last half, the poorest-performing sectors outside of banks were most connected to global growth - materials, energy and industrial companies.

"There is a growing realization that the global economy is in jeopardy," said Bruce Bittles, chief investment strategist at Robert W. Baird & Co in Nashville. "There is uncertainty in every corner of the world."

That uncertainty fed substantial volatility in 2011. Despite the S&P's flat performance this year, there were 66 trading days when stocks moved in a 2 percent range. In 2008, when Lehman Brothers collapsed during a global financial crisis, there were more than 130 trading days when stocks swung that much. But that led to a flight from equities by retail investors.

U.S. equity funds had outflows in every month since May. More than $483 billion left U.S. mutual funds in 2011 through the year's second-to-last week, even though the U.S. market outperformed foreign stocks late in the game.

BEATING GLOBAL RIVALS

The S&P 500 ended the year off a scant 0.003 percent, the closest it has come to unchanged since 1947, according to Standard & Poor's. The Dow Jones industrial average (.DJI) finished 2011 with a 5.5 percent gain, while the Nasdaq Composite Index (.IXIC) slipped 1.8 percent.

In contrast, the MSCI world stocks index (.MIWD00000PUS) fell 9 percent, while the FTSEurofirst-300 index (.FTEU3) slid nearly 11 percent.

The darlings in the emerging markets fared the worst. China's Shanghai Composite index (.SSEC) lost 22 percent, India's BSE (.BSESN) sank 25 percent, and Brazil's Bovespa (.BVSP) dropped 18 percent.

Strategists say the U.S. stock market may benefit from reasonable economic growth and attractive market valuation. The S&P 500 is expected to rise 6 percent by the end of 2012, according to the most recent poll of Wall Street strategists.

When Wall Street gets back to work on Tuesday, it will face a holiday-shortened week and a slew of economic indicators. The most crucial numbers will come on Friday when the government will release the December non-farm payrolls report. Economists polled by Reuters expect a December gain of 150,000 jobs, compared with an increase of 120,000 jobs in November.

Volatility is likely to persist through early 2012 because of the uncertainty in Europe and rising concern about slowed earnings growth due to recent revisions.

The S&P 500's price-to-earnings ratio - what investors are willing to pay for a dollar of earnings - is under 12, below the 25-year average of 15. In weaker markets like Germany's DAX, the figure is below 9.

"We're building in a massive recession into these numbers," said Marc Pado, U.S. market strategist at Cantor Fitzgerald & Co. in San Francisco.

U.S. companies cutting earnings' outlooks recently outpaced those raising theirs by the greatest ratio in 10 years. Some sectors, such as materials, have seen a sharp drop in forecasts for the fourth quarter, Thomson Reuters data showed.

Last week, downbeat earnings from Oracle Corp (ORCL.O) shook confidence in the tech sector's health before the quarterly earnings season's start in January. Oracle joined a growing list of companies, including some of technology's biggest names, whose results and outlooks have set off alarm bells.

Next year, S&P 500 earnings are seen rising 9.9 percent, down from an estimate of 13 percent in October.

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Graphics: Global markets in 2011: Volatile and Unpredictable http://r.reuters.com/xut75s

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RECESSION FEARS

Many economists believe the euro zone is already in recession. They forecast that the economies of the 17-nation bloc will stagnate in 2012 after contracting in this year's fourth quarter and the first quarter of the next.

Investors are worried that Italy and Spain will have to keep refinancing borrowings at unsustainable levels early next year, which could escalate the crisis.

The correlation between the U.S. stock market and the euro skyrocketed in 2011 as investors tied bets on risky assets to the euro's moves. That trend ebbed as equities rallied near the end of the year, but it is likely to flare up again.

So far the U.S. economy has stayed on course for moderate growth. Economists expect it to expand by about 2.1 percent next year. But it is unclear how a slowdown in the rest of the world will affect the economy stateside.

The key may be China rather than Europe.

"China is the 800-pound gorilla in the room and is probably the most important country to watch in terms of their contribution to global growth," said Michael Sheldon, chief market strategist at RDM Financial in Westport, Connecticut.

Chinese business confidence is weakening. A survey showed export orders fell for the first time in nearly three years.

The drop in materials shares in 2011's second half reflects worry about declining activity overseas. The S&P Materials Index (.GSPM) lost nearly 14 percent in the last six months.

GRIDLOCK SHOCK

One of the pivotal events of 2011 was the downgrade of the United States' perfect triple-A credit rating. Standard & Poor's cited congressional bickering as the reason for the downgrade.

August's stalemate in Washington over raising the debt ceiling sparked a selloff that accelerated after the downgrade.

Investors expect the gridlock in Congress to get worse as the U.S. presidential election approaches in November. The election is likely to be close, which will not make legislative efforts to tackle high debt levels and weak demand any easier.

Rancor was in view again in December as Congress struggled to pass a two-month extension of U.S. payroll-tax cuts.

"There will be less certainty about taxation and regulation so that will inhibit business formation and business growth," said Brian Battle, a trader at Performance Trust Capital Partners in Chicago.

Goldman Sachs sees global growth highly susceptible in 2012 to even minor shocks - and those shocks may be political.

"Slowing growth (and in places outright contraction), public-sector cuts, and a renegotiation of the social compact between state and society in different parts of the world is an environment ripe for political turmoil," Goldman said in a note to clients.

(Reporting By Edward Krudy; Editing by Jan Paschal)

Source: http://us.rd.yahoo.com/dailynews/rss/stocks/*http%3A//news.yahoo.com/s/nm/20111230/bs_nm/us_usa_stocks_weekahead

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Paul's surge may prompt a new look from GOP voters (The Arizona Republic)

Share With Friends: Share on FacebookTweet ThisPost to Google-BuzzSend on GmailPost to Linked-InSubscribe to This Feed | Rss To Twitter | Politics - Top Stories Stories, News Feeds and News via Feedzilla.

Source: http://news.feedzilla.com/en_us/stories/politics/top-stories/179960951?client_source=feed&format=rss

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Friday, 30 December 2011

Scientists fixate on Ric-8 to understand trafficking of popular drug receptor targets

Scientists fixate on Ric-8 to understand trafficking of popular drug receptor targets [ Back to EurekAlert! ] Public release date: 28-Dec-2011
[ | E-mail | Share Share ]

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center

Half the drugs used today target a single class of proteins and now scientists have identified an important molecular player critical to the proper workings of those proteins critical to our health.

A protein known as Ric-8 plays a vital role, according to new results from a team led by Gregory Tall, Ph.D., assistant professor of Pharmacology and Physiology at the University of Rochester Medical Center. The work was published recently in Science Signaling.

What you see, what you smell, how you feel molecules known as G-protein coupled receptors and their prime targets, G proteins, are key to those and many other processes that are ubiquitous in our bodies. These proteins serve as the targets of drugs used to treat conditions like cancer, diabetes, depression, allergies, and heart disease.

These receptors normally weave themselves throughout the cell membrane, with one part protruding from the outside of a cell, and the rest of the protein inside the cell. When a compound like a drug or a hormone attaches to a receptor on the cell surface, it affects the G protein bound to the portion of the receptor that is inside the cell, triggering a cascade of signals that make life possible or improve health, in the case of a drug, or perhaps hurting health in the case of a toxin.

Previously, Tall discovered the existence of Ric-8 and learned that it binds to G proteins, which are made inside cells and have to make their way to the cell's outer edge, the membrane, to work correctly. In the new work, his team found that Ric-8 is a chaperone that G proteins need to be transported to the cell membrane. When Ric-8 is knocked out, G proteins don't work as they should and are destroyed.

"G proteins are involved in many biological processes how we see and taste, how our heart beats, even our mood," said Tall. "It's a very important class of proteins. Ric-8 is the chaperone that gets G proteins where they need to be, to the cell membrane. Without it, many of these proteins end up destroyed within the cell."

"Understanding more precisely how this important class of proteins operates in the body can perhaps make many of the drugs we use today more effective for patients," Tall added.

To do the study, Tall and colleagues had to devise a system where they could study the molecules in action. In living animals such as mice, when Ric-8 is knocked out completely, the animals die. So the team worked to identify a stem cell line in which the Ric-8 gene was knocked out, so they could study G protein function in the absence of Ric-8.

###

The first author was graduate student Meital Gabay. Other authors at the University include Mary Pinter, an undergraduate student now at the University of Colorado at Denver; technical associate Forrest Wright, now at SUNY Upstate Medical University; and graduate student PuiYee Chan. The team worked with scientists at Regeneron Pharmaceuticals who created the "knockout" mice used in the study.

Funding for the work came from the National Institute of General Medical Sciences and from the Empire State Stem Cell Board.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Scientists fixate on Ric-8 to understand trafficking of popular drug receptor targets [ Back to EurekAlert! ] Public release date: 28-Dec-2011
[ | E-mail | Share Share ]

Contact: Tom Rickey
tom_rickey@urmc.rochester.edu
585-275-7954
University of Rochester Medical Center

Half the drugs used today target a single class of proteins and now scientists have identified an important molecular player critical to the proper workings of those proteins critical to our health.

A protein known as Ric-8 plays a vital role, according to new results from a team led by Gregory Tall, Ph.D., assistant professor of Pharmacology and Physiology at the University of Rochester Medical Center. The work was published recently in Science Signaling.

What you see, what you smell, how you feel molecules known as G-protein coupled receptors and their prime targets, G proteins, are key to those and many other processes that are ubiquitous in our bodies. These proteins serve as the targets of drugs used to treat conditions like cancer, diabetes, depression, allergies, and heart disease.

These receptors normally weave themselves throughout the cell membrane, with one part protruding from the outside of a cell, and the rest of the protein inside the cell. When a compound like a drug or a hormone attaches to a receptor on the cell surface, it affects the G protein bound to the portion of the receptor that is inside the cell, triggering a cascade of signals that make life possible or improve health, in the case of a drug, or perhaps hurting health in the case of a toxin.

Previously, Tall discovered the existence of Ric-8 and learned that it binds to G proteins, which are made inside cells and have to make their way to the cell's outer edge, the membrane, to work correctly. In the new work, his team found that Ric-8 is a chaperone that G proteins need to be transported to the cell membrane. When Ric-8 is knocked out, G proteins don't work as they should and are destroyed.

"G proteins are involved in many biological processes how we see and taste, how our heart beats, even our mood," said Tall. "It's a very important class of proteins. Ric-8 is the chaperone that gets G proteins where they need to be, to the cell membrane. Without it, many of these proteins end up destroyed within the cell."

"Understanding more precisely how this important class of proteins operates in the body can perhaps make many of the drugs we use today more effective for patients," Tall added.

To do the study, Tall and colleagues had to devise a system where they could study the molecules in action. In living animals such as mice, when Ric-8 is knocked out completely, the animals die. So the team worked to identify a stem cell line in which the Ric-8 gene was knocked out, so they could study G protein function in the absence of Ric-8.

###

The first author was graduate student Meital Gabay. Other authors at the University include Mary Pinter, an undergraduate student now at the University of Colorado at Denver; technical associate Forrest Wright, now at SUNY Upstate Medical University; and graduate student PuiYee Chan. The team worked with scientists at Regeneron Pharmaceuticals who created the "knockout" mice used in the study.

Funding for the work came from the National Institute of General Medical Sciences and from the Empire State Stem Cell Board.



[ Back to EurekAlert! ] [ | E-mail | Share Share ]

?


AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2011-12/uorm-sfo122711.php

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johnleesandiego: RT @youngandfoodish: if a new london resto did only macaroni & cheese and did it better than anyone else who amongst you would NOT go?

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A Look at the Nevada Gaming Commission&#39;s Online Poker ...

Nevada Online Poker Regulations

The Nevada Gaming Commission's approval of online poker regulations Dec. 22 sets the stage for legal, licensed and regulated Internet poker to debut in the United States in the next year. However, the scope of the performance is still very much in question.

Whether the regulations are used under a national network, intrastate within only Nevada, or interstate between states under a Nevada umbrella, will depend on the progress of a federal bill and state efforts in 2012.

Whatever the future of online poker is, Nevada wants to be at the center just as it is in the world of bricks-and-mortar gambling. These regulations, which were asked for by legislation passed earlier this year in the state legislature, give Nevada a head start at establishing the framework for regulating online poker no matter what form it takes.

The Nevada Gaming Commission already has begun accepting applications for companies to operate Internet poker sites, including from Caesars Entertainment and Boyd Gaming. The companies that receive licenses will be free to begin offering play to people living in Nevada.

For companies that already own regular Nevada gaming licenses, the approval process is expected to be less than 90 days. It may take a little longer to form the internal controls necessary to implement the regulations. The first sites could begin serving people inside Nevada during the second half of 2012.

If a federal bill does pass, it is expected that states and Indian territories will be the regulators. That is the plan currently laid out in Rep. Joe Barton's bill. Once a federal law is in place, Nevada will be ready to go and have companies pre-approved. Some states, like New Jersey and California, may want to handle their own regulation. Others may want to let Nevada oversee online poker in their state.

"Nevada is essentially moving ahead without a federal law," said John Pappas, executive director of the Poker Players Alliance. "Should it become federal law, I think Nevada will be in the position to be one of the first states certified to issue licenses. I think a lot of states would rather not take the regulatory burden upon themselves and would say what's good enough for Nevada is good enough for us."

Liquidity is an issue with intrastate poker in Nevada, which has a population of about three million with additional people always in the state as tourists. However, with the popularity of live poker in places like Las Vegas, it might be the case that a higher percentage of people in Nevada are interested in playing poker than in other states.

If a federal law does not come along in the next couple of years, other states could end up officially legalizing online poker and joining Nevada to combine player pools across states. This option was made possible by the Justice Department's recent announcement that the Wire Act, which prevents wagers across state lines, applies only to sports betting.

The approved regulations are important because many of them could end up being the rules used by the largest regulatory agency after federal legislation.

Some noteworthy aspects of the regulations:

  • Player fund transfers are not allowed.
  • Affiliates are allowed.
  • Operators must ensure that players have only one account.
  • Operators may pay a fixed sum to celebrity players for marketing purposes as long as the operator does not profit beyond the rake.
  • Promotional credits or bonus credits offered by the operator are allowed.
  • An operator must maintain a reserve of cash, cash equivalents, an irrevocable letter of credit, bond, or combination thereof, equal to the sum of all players' funds.
  • Any compensation received by an operator for conducting any game in which the operator is not party to a wager shall be no more than 10 percent of all funds wagered in each hand.

The regulations aren't final. The Nevada Gaming Commission may decide to add or amend the rules at any time. Pappas said the PPA had not yet looked deeply enough into the regulations to determine if the organization had any concerns from a player standpoint.

Nevada having regulations in place to govern online poker could help with congressmen who remain on the fence regarding the issue.

"I think it shows Congress that the most prominent gaming state in the country is ready to regulate this activity and believes it can be regulated," Pappas said. "I think that gives lawmakers some comfort that this can be appropriately regulated by an accredited regulating body."

Follow PokerNews on Twitter for up-to-the-minute news.

Comments

Source: http://www.pokernews.com/news/2011/12/nevada-gaming-commission-s-online-poker-regulations-11714.htm

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Thursday, 29 December 2011

Ben Nelson's planned retirement: A big blow to Dems? (The Week)

New York ? The Nebraska senator won't seek a third term, raising questions about the Left's chances of holding onto its slim Senate majority

Senate Majority Leader Harry Reid may have trouble hanging onto his majority title in the 113th Congress. On Tuesday, Sen. Ben Nelson (D-Neb.) became the latest moderate Democrat (following Kent Conrad and Jim Webb, among others) to announce that he won't seek another term in the 2012 election. Nelson, who faced an uphill battle for a third term, is the sole Democrat in Nebraska's five-member congressional delegation, and many political analysts believe his red-state seat could now be a relatively easy Republican pickup. The GOP is working hard to wrest control of the Senate from the Dems in 2012, and only has to net four seats to flip the Dems' 53-47 majority in the 100-member Senate. Is Nelson's retirement a "significant blow" to Dems, or no biggie since he would have likely lost his re-election bid anyway?

This is a big loss for Dems:?Nelson's retirement "puts Republicans one seat closer to a majority," Cook Political Report's Jennifer Duffy?tells Bloomberg. I simply "don't see a path to victory for Democrats in Nebraska." Nelson is hardly perfect, Rothenberg Political Report's Nathan Gonzales tells Bloomberg, but he was the Dems' best bet in the Cornhusker State. And remember, Democrats are already "defending eight out of the 10 most competitive seats in the country." This is a "significant blow" in the Left's quest to keep the Senate.
"Nelson's retirement hurts Senate Dems' in 2012"

But Nelson would have lost anyway: This isn't such a big deal, says Ed Morrissey at Hot Air. Though I'm reluctant "to underestimate the power of incumbency," you can bet Nelson wouldn't have been re-elected in this "very red state." "The man couldn't even eat a pizza in peace after casting a decisive vote for ObamaCare and tossing his pro-life credentials into the wastebasket by doing so." He would have surely been replaced by "a credible Republican candidate." This development doesn't change "the calculus in Nebraska."
"Breaking: Nelson to retire"

This might even be good for Dems:?Of course, this looks "like a very tough break for Team Blue,"?says David Nir at the?Daily Kos. But?there could be "a silver lining."?If "Nelson really had no hope of winning another term, then a ton of resources would have been wasted on a futile attempt to save him." Now, if losing his seat is a foregone conclusion, Democrats can focus on defending seats they actually have a chance of keeping, not to mention helping new candidates, like Shelley Berkley in Nevada and Elizabeth Warren in Massachusetts, who stand a chance of picking up new seats.
"NE-Sen: Democrat Ben Nelson reportedly will announce retirement"

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Source: http://us.rd.yahoo.com/dailynews/rss/politicsopinion/*http%3A//news.yahoo.com/s/theweek/20111228/cm_theweek/222889

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Cranky croc steals Aussie zoo worker's lawn mower (AP)

SYDNEY ? A giant saltwater crocodile named Elvis with an apparent affinity for household machinery charged at an Australian reptile park worker Wednesday before stealing his lawn mower.

Tim Faulkner, operations manager at the Australian Reptile Park, north of Sydney, was one of three workers tending to the lawn in Elvis' enclosure when he heard reptile keeper Billy Collett let out a yelp. Faulkner looked up to see the 16-foot (5-meter), 1,100-pound (500-kilogram) crocodile lunging out of its lagoon at Collett, who warded the creature off with his mower.

"Before we knew it, the croc had the mower above his head," Faulkner said. "He got his jaws around the top of the mower and picked it up and took it underwater with him."

The workers quickly left the enclosure. Elvis, meanwhile, showed no signs of relinquishing his new toy and sat guarding it closely all morning.

Eventually, Faulkner realized he had no other choice but to go back in after the mower.

Collett lured Elvis to the opposite end of the lagoon with a heaping helping of kangaroo meat while Faulkner plunged, fully clothed, into the water. Before grabbing the mower, however, he had to search the bottom of the lagoon for two 3-inch (7-centimeter) teeth Elvis lost during the encounter. He quickly found them and escaped from the pool, unharmed and with mower in tow.

Though many may question the wisdom of going after a couple of teeth with a massive crocodile lurking just feet away, Faulkner said finding them was critical. "They clog up the filter systems," he said.

And, perhaps more important, he said, "They're a nice souvenir."

Elvis has a history of cranky behavior and has occasionally lunged at staff before, though this is the first time he has stolen something from one of the workers. The croc was initially captured in the northern Australian city of Darwin, where he had been attacking fishing boats. He was then moved to a crocodile farm, where he proceeded to kill his two crocodile girlfriends.

In 2008, he was moved to the reptile park, where he has enjoyed solitary confinement in his own enclosure.

"When they are the dominant croc, they're just full of testosterone," Faulkner said. "He's got his beautiful own yard, he wants to be a solitary creature. He's happy."

Despite having to give up the lawn mower, Elvis was clearly pleased with himself, Faulkner said.

"He's beaten us today ... he's kingpin," Faulkner said. "He's going to be walking around with his chest puffed out all day."

As for the staff at the reptile park?

"I can't lie, the bosses are not going to be happy about the cost of a new lawn mower," Faulkner said with a laugh. "(But) we love it. No one's injured ... and when you get scared and it all turns out to be good, it's actually quite enjoyable."

Source: http://us.rd.yahoo.com/dailynews/rss/oceania/*http%3A//news.yahoo.com/s/ap/20111228/ap_on_re_as/as_australia_klepto_crocodile

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Italy fines Apple $1.2 mln over misleading support claims (Digital Trends)

Apple Store Milan

Italian antitrust regulators have fined Apple some ?900,000 (about US$1.2 million) (Italian) for failing to to inform Italian customers of their legal right to two years? of technical support for their products. As a result, regulators found many customers were mislead into paying for AppleCare protection for coverage beyond the first year of ownership.

AppleCare Protection plans typically offer two years of coverage for iPhone and iPad products, and three years for notebook and desktop computers. For mobile products, that means Italian customers buying AppleCare were effectively lured into paying for coverage they were entitled to under Italian law.

Some ?400,000 of the penalty was for Apple failing to inform consumers at point of sale or on their Web sites of the statutory two-year guarantee required under Italian law. An additional ?500,000 penalty was assessed for Apple then offering its paid-for AppleCare plans for technical support after the first year. In addition, Apple is being required to change its AppleCare packaging to reflect the two-year warranty period mandated by Italian consumer code, as well as put a notice on its Web site informing Italian customers of the settlement.

Apple has not yet responded to requests for comment on the ruling. It?s not clear whether Italian customers who purchased additional AppleCare coverage for their devices will be reimbursed, see their terms of coverage extended, or receive any form of compensation.

This article was originally posted on Digital Trends

More from Digital Trends

Apple Delays International iPad Rollout by One Month

Foxconn to expand iPhone production facility, set to become world?s largest

Tech firm honors Steve Jobs with bronze statue of late Apple boss

iPad dust may have caused China factory blast, tablet supplies could be affected

Source: http://us.rd.yahoo.com/dailynews/rss/europe/*http%3A//news.yahoo.com/s/digitaltrends/20111227/tc_digitaltrends/italyfinesapple12mlnovermisleadingsupportclaims

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Wednesday, 28 December 2011

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Source: http://www.oleole.com/blogs/sonia994/posts/watch-detroit-pistons-vs-indiana-pacers-live-stream-free-online-nba-hd-broadcast-26-dec

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Gold Demand in India Sluggish as Rupee Slide Supports Price

A fall in overseas gold market failed to lift physical demand in India, the world's top consumer, as the depreciating rupee kept prices steady in the local market.

* Demand took a hit as buying declined during year-end holidays and the month is considered inauspicious for purchases, dealers said.

* At 3:05 p.m, the most-active February gold contract on the Multi Commodity Exchange was unchanged at 27,651 rupees per 10 grams.

* "Rupee has gone down considerably, and general feel among consumers is that gold will fall from the current levels. That's why demand is not improving," said a Mumbai-based dealer with a private bank dealing in bullion.

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* "We can see improvement in demand if prices go down to $1,560 per ounce level. Even price rise above $1,650 level will attract buyers. Then people will change their medium term view," the dealer said. International gold was trading at $1,585.

* The on-going Khar mass also affected on purchases, dealers said. Khar Mass is a month in the Hindu calendar from December 16 to January 14 which is considered inauspicious for gold buying and starting new ventures.

* International spot gold edged lower on Wednesday, tracking falls in industrial metals and equities, as concerns about global economic growth weighed on market sentiment amid thin year-end trading volumes.

* The rupee, which plays an important role in determining the landed cost of dollar-quoted gold, weakened to 53.36 to the dollar from 53.015/025 at Tuesday's close, weighed by dollar demand from oil companies and weak shares.

* A Reuters poll earlier this month of 20 hedge fund managers, economists and traders showed international spot gold prices are expected to fall below $1,500 an ounce over the next three months and they are unlikely to retest September's all-time highs until later 2012 at the earliest.

At 1:15 p.m., the following were prices in rupees being quoted by RiddiSiddhi Bullion in the spot market:

Gold .999/10 grams 27,575 27,560

Silver .999/kg 52,100 52,230

At 2:38 p.m., following were prices (in rupees) on the Multi Commodity Exchange of India Ltd.

Feb gold 27,657 +6

Mar silver 52,705 -6

Source: http://www.ibtimes.com/articles/273468/20111228/gold-demand-india-sluggish-rupee-local-market.htm

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'Games Of Thrones' Director Alan Taylor To Helm 'Thor 2' (omg!)

Chris Hemsworth steps out at the premiere of "Thor" at the El Capitan Theatre in Los Angeles on May 2, 2011 -- Getty Premium

"Thor 2" has found its director.

Alan Taylor will replace Patty Jenkins at the helm of the superhero sequel, according to Deadline, which was first to report the news.

PLAY IT NOW: Trailer: ?The Avengers?

Taylor, an accomplished TV director, is best known for his work on HBO's "Game of Thrones," as well as credits on small screen hits including "Boardwalk Empire," "Mad Men" and "Nurse Jackie."

Jenkins, director of 2003's crime drama "Monster," was originally slated to direct the film, but was removed from the project earlier this month following rumored creative differences with Marvel.

VIEW THE PHOTOS: Superhero Star Chris Evans

The highly anticipated sequel, featuring returning star Chris Hemsworth as the hammer-wielding Norse god, is slated for theatrical release on November 13, 2013.

Copyright 2011 by NBC Universal, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.

Source: http://us.rd.yahoo.com/dailynews/rss/entertainment/*http%3A//us.rd.yahoo.com/dailynews/external/omg_rss/rss_omg_en/news_games_thrones_director_alan_taylor_helm_thor2_183118021/44007393/*http%3A//omg.yahoo.com/news/games-thrones-director-alan-taylor-helm-thor-2-183118021.html

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Pakistan president vows defiance as crises mount (Reuters)

GARHI KHUDA BAKSH, Pakistan (Reuters) ? Pakistan's embattled but defiant President Asif Ali Zardari used the fourth anniversary of the death of his wife Benazir Bhutto to ensure supporters he would not resign in the face of numerous crises building around him.

Zardari, who became president after the former prime minister was killed in 2007 following her return from self-imposed exile, is facing perhaps the greatest threat to the government.

In a jab at the Supreme Court, which is considering an investigation into a memo asking the United States for help against the country's powerful military and which could implicate Zardari, he asked about the as yet unsolved case of his wife's assassination.

"People ask what happened to Benazir Bhutto's case," he said. "I ask (Chief Justice) Iftikhar Chaudhry: what happened to Benazir Bhutto's case?"

No one has yet been charged with her assassination at a huge rally outside Islamabad.

Police estimated Tuesday's crowd at more than 70,000.

Colorful banners sprouted from the throng, which spread out beneath the white, marble mausoleum that contains the bodies of Pakistan's most famous political family.

Speaking from behind bulletproof glass, Zardari appeared relaxed and healthy, likely calm rumors of his ill health.

He flew to Dubai on Dec 6 complaining of chest pains. Party members there told Reuters he had suffered a transient ischemic attack, a stroke-like attack that leaves no permanent brain damage. He returned on Dec 19.

Members of Zardari's Pakistan People's Party say opponents are working with the Supreme Court and the army to bring down the government.

The death anniversary came the same day the Supreme Court began deliberations on whether it could open its own investigation into the so-called "memogate" scandal.

It also came two days after cricketer-turned-politician Imran Khan brought at least 100,000 people into the streets of Karachi in a rally that increases pressure the government and cements his standing as a political force.

The memogate hearing, which was adjourned without any decision, is likely to be front-page news on Wednesday, reflecting the intense interest in incremental developments in the crisis.

CALL FOR INVESTIGATION

It involves the publication an unsigned memo seeking Washington's help to rein in the military after U.S. forces found and killed al Qaeda leader Osama bin Laden in Pakistan in May.

Pakistan's then ambassador to the United States, Husain Haqqani, has been accused of writing the memo on behalf of the government. He denies involvement but has resigned pending an investigation.

Chief of Army Staff General Asfaq Kayani has called for an investigation into the memo, which has set off a flurry of speculation of a rift between the government and the army which has ruled Pakistan for almost half of its 64-year history.

The political crisis also comes as ties between the United States and Pakistan drop to their lowest point in decades following a NATO cross-border attack on Nov 26 that killed 24 Pakistani soldiers. A U.S. report on the incident blamed both sides for poor communications and bad maps.

The incident infuriated Pakistan's army, which is demanding an apology from President Barack Obama, and led to the closure of supply lines for coalition forces fighting in Afghanistan.

The army has denied planning to take power but Prime Minister Yusuf Raza Gilani has added to the intrigue and confusion.

Last week he surprised many by implicitly suggesting the military was a "state within a state" before reversing himself on Monday night and saying he was "happy" with Kayani and would not fire him or the head of the Inter-Services Intelligence agency, as some media reports claimed.

Zardari "struck a defiant note, but refrained from attacking the military establishment," at the rally, said security analyst Imtiaz Gul. "This comes a day after Gilani also backed down, and based on that this smacks of some sort of 'backdown' on the part of the government."

Party members on the scene were upbeat.

"The army or the Supreme Court can do nothing to the government and our party," said Ali Gohar, 45, a PPP worker from the town of Sukkur who has come to pay homage to Bhutto.

"The PPP has the blood of martyrs in its foundations and we will support it as long as we live."

(Writing by Chris Allbritton; Additional reporting by Qasim Nauman and Faisal Aziz in ISLAMABAD; Editing by Nick Macfie)

Source: http://us.rd.yahoo.com/dailynews/rss/asia/*http%3A//news.yahoo.com/s/nm/20111227/wl_nm/us_pakistan_politics

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Tuesday, 27 December 2011

Hackers target global analysis company (CNN)

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L'atelier bnp paribas e commerce insider the rise and fall of group buying in China

In first half of this year, the domestic group buying market was cultivating in a vibrant scene and the landscape of group buying websites has been intermittently under convulsion.

The gr

In first half of this year, the domestic group buying market was cultivating in a vibrant scene and the landscape of group buying websites has been intermittently under convulsion.

The grim reality is such a crowded market, fueled by venture capitals and vicious competition, filled with counterfeit products and not guaranteed offline service, is shrinking and becoming a grotesque gallery of layoffs, closings, late payments, dissatisfied clients, and shattered dreams.

After all, consumers still have the local business demands. The market is there and won?t be gone with wind.

Other topics :
The growth of China online luxury
2) Coach?s online store on Taobao Mall
3) Yoox promote China local designers via e-commerce
4) 360buy raised threshold of its free delivery policy
5) China online cosmetics platforms go more vertical or horizontal
6) Will China group buying market is a just a an online Titantic?

1. Onl

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London Pussycats : Happy New Year

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